BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 25495

Title: Structure and dynamics of the acidosis-resistant a162H mutant of the switch region of troponin I bound to the regulatory domain of troponin C   PubMed: 25996354

Deposition date: 2015-02-20 Original release date: 2015-06-01

Authors: Pineda Sanabria, Sandra; Robertson, Ian; Sykes, Brian

Citation: Pineda Sanabria, Sandra; Robertson, Ian; Sykes, Brian. "Structure and dynamics of the acidosis-resistant A162H mutant of the switch region of troponin I bound to the regulatory domain of troponin C"  Biochemistry 54, 3583-3593 (2015).

Assembly members:
cNTnC, polymer, 89 residues, 10070.361 Da.
cTnIA162H, polymer, 27 residues, 3072.655 Da.
entity_CA, non-polymer, 40.078 Da.

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli

Entity Sequences (FASTA):
cNTnC: MDDIYKAAVEQLTEEQKNEF KAAFDIFVLGAEDGCISTKE LGKVMRMLGQNPTPEELQEM IDEVDEDGSGTVDFDEFLVM MVRCMKDDS
cTnIA162H: RRVRISADAMMQALLGARHK ESLDLRA

Data sets:
Data typeCount
13C chemical shifts239
15N chemical shifts83
1H chemical shifts731

Additional metadata:

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Related Database Links:

BMRB 25035

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