BMRB Entry 25588
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PDB ID: 2n27
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_anomalous, AVS_full, LACS, SPARTA
BMRB Entry DOI: doi:10.13018/BMR25588
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Title: Direct attack of vanilloids on the regulation of the pain receptor TRPV1 PubMed: 27339229
Deposition date: 2015-04-29 Original release date: 2016-06-30
Authors: Hetenyi, Anasztazia; Nemeth, Lukacs; Weber, Edit; Szakonyi, Gerda; Winter, Zoltan; Josvay, Katalin; Olah, Zoltan; Martinek, Tamas
Citation: Hetenyi, Anasztazia; Nemeth, Lukacs; Weber, Edit; Szakonyi, Gerda; Winter, Zoltan; Josvay, Katalin; Olah, Zoltan; Martinek, Tamas. "Competitive inhibition of TRPV1 - calmodulin interaction by vanilloids" FEBS Lett. 590, 2768-2775 (2016).
Assembly members:
Calmodulin, polymer, 148 residues, 16721.465 Da.
entity_CA, non-polymer, 40.078 Da.
entity_4DY, non-polymer, 305.412 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
Calmodulin: ADQLTEEQIAEFKEAFSLFD
KDGDGTITTKELGTVMRSLG
QNPTEAELQDMINEVDADGN
GTIDFPEFLTMMARKMKDTD
SEEEIREAFRVFDKDGNGYI
SAAELRHVMTNLGEKLTDEE
VDEMIREADIDGDGQVNYEE
FVQMMTAK
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 1205 |
| 15N chemical shifts | 421 |
| 1H chemical shifts | 1663 |
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