BMRB Entry 25595
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PDB ID: 2n2c
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS, SPARTA
BMRB Entry DOI: doi:10.13018/BMR25595
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Title: NMR Structure of TDP-43 prion-like hydrophobic helix in DPC
Deposition date: 2015-05-06 Original release date: 2015-11-19
Authors: Lim, Liang Zhong; Song, Jianxing
Citation: Lim, Liang Zhong; Song, Jianxing. "ALS-causing mutations significantly perturb the self-assembly and interaction with nucleic acid of the intrinsically-disordered prion-like domain of TDP-43" Plos Biology ., .-..
Assembly members:
entity, polymer, 43 residues, 4336.979 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
entity: MGGGMNFGAFSINPAMMAAA
QAALQSSWGMMGMLASQQNQ
SGP
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 84 |
| 15N chemical shifts | 40 |
| 1H chemical shifts | 188 |
Additional metadata:
Related Database Links:
| DBJ | BAC27753 BAD96474 BAE21557 BAE26823 BAE32189 |
| EMBL | CAB43367 CAG31358 CAG38565 CAH92854 CAJ81570 |
| GB | AAA70033 AAH12873 AAH25544 AAH27772 AAH31126 |
| REF | NP_001026049 NP_001039950 NP_001127597 NP_001231687 NP_001231688 |
| SP | Q13148 Q28F51 Q5R5W2 Q5ZLN5 Q921F2 |
| TPG | DAA21291 |
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