BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 25652

Title: Structure of PTB RRM1(41-163) bound to an RNA stemloop containing a structured loop derived from viral internal ribosomal entry site RNA

Deposition date: 2015-06-08 Original release date: 2016-08-08

Authors: Maris, Christophe; Jayne, Sandrine; Damberger, Fred; Ravindranathan, Sapna; Allain, Frederic

Citation: Maris, Christophe; Jayne, Sandrine; Damberger, Fred; Ravindranathan, Sapna; Allain, Frederic. "C-terminal helix folding upon pyrimidine-rich hairpin binding to PTB RRM1. Implications for PTB function in Encephalomyocarditis virus IRES activity."  To be Published ., .-..

Assembly members:
PTBRRM1, polymer, 123 residues, 13375.287 Da.
RNA_(5'-R(*GP*GP*GP*AP*CP*CP*UP*GP*GP*UP*CP*UP*UP*UP*CP*CP*AP*GP*GP*UP*CP*CP*C)-3'), polymer, 23 residues, 7308.393 Da.

Natural source:   Common Name: human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli

Entity Sequences (FASTA):
PTBRRM1: GNDSKKFKGDSRSAGVPSRV IHIRKLPIDVTEGEVISLGL PFGKVTNLLMLKGKNQAFIE MNTEEAANTMVNYYTSVTPV LRGQPIYIQFSNHKELKTDS SPNQARAQAALQAVNSVQSG NLA
RNA_(5'-R(*GP*GP*GP*AP*CP*CP*UP*GP*GP*UP*CP*UP*UP*UP*CP*CP*AP*GP*GP*UP*CP*CP*C)-3'): GGGACCUGGUCUUUCCAGGU CCC

Data sets:
Data typeCount
13C chemical shifts535
15N chemical shifts119
1H chemical shifts1013
residual dipolar couplings70

Additional metadata:

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Related Database Links:

UNP K7ES59

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