BMRB Entry 25987
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PDB ID: 2nbp
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_anomalous, AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR25987
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Title: Solution structure of the T119M variant of transthyretin in its monomeric state PubMed: 27885756
Deposition date: 2016-03-09 Original release date: 2017-05-08
Authors: Kim, Jin Hae; Oroz, Javier; Zweckstetter, Markus
Citation: Kim, Jin Hae; Oroz, Javier; Zweckstetter, Markus. "Structure of Monomeric Transthyretin Carrying the Clinically Important T119M Mutation." Angew. Chem. Int. Ed. Engl. 55, 16168-16171 (2016).
Assembly members:
T119M_M-TTR, polymer, 127 residues, 13809.627 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
T119M_M-TTR: GPTGTGESKCPLMVKVLDAV
RGSPAINVAVHVFRKAADDT
WEPFASGKTSESGELHGLTT
EEEFVEGIYKVEIDTKSYWK
ALGISPMHEHAEVVFTANDS
GPRRYTIAAMLSPYSYSTMA
VVTNPKE
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 381 |
| 15N chemical shifts | 114 |
| 1H chemical shifts | 798 |
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