BMRB Entry 26513
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR26513
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Title: The Apo-structure of the Low Molecular Weight Protein-tyrosine Phosphatase A (MptpA) from Mycobacterium tuberculosis Allows for Better Target-specific Drug Development PubMed: 22888002
Deposition date: 2015-02-17 Original release date: 2015-02-24
Authors: Stehle, Tanja; Sreeramulu, Sridhar; Lohr, Frank; Richter, Christian; Saxena, Krishna; Jonker, Hendrik; Schwalbe, Harald
Citation: Stehle, Tanja; Sreeramulu, Sridhar; Lohr, Frank; Richter, Christian; Saxena, Krishna; Jonker, Hendrik; Schwalbe, Harald. "The Apo-structure of the Low Molecular Weight Protein-tyrosine Phosphatase A (MptpA) from Mycobacterium tuberculosis Allows for Better Target-specific Drug Development" J. Biol. Chem. 287, 34569-34582 (2012).
Assembly members:
MptpA, polymer, 167 residues, Formula weight is not available
Natural source: Common Name: Mycobacterium tuberculosis Taxonomy ID: 1773 Superkingdom: Bacteria Kingdom: not available Genus/species: Mycobacterium tuberculosis
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
MptpA: GAMGMSDPLHVTFVCTGNIC
RSPMAEKMFAQQLRHRGLGD
AVRVTSAGTGNWHVGSCADE
RAAGVLRLHGYPTDHRAAQV
GTEHLAADLLVALDRNHARL
LRQLGVEAARVRMLRSFDPR
SGTHALDVEDPYYGDHSDFE
EVFAVIESALPGLHDWVDER
LARNGPS
- assigned_chemical_shifts
- heteronucl_NOEs
- heteronucl_T1_relaxation
- heteronucl_T2_relaxation
- order_parameters
| Data type | Count |
| heteronuclear NOE values | 132 |
| T1 relaxation values | 136 |
| T2 relaxation values | 133 |
| order parameters | 119 |