BMRB Entry 30206
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PDB ID: 5u5s
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_anomalous, AVS_full
BMRB Entry DOI: doi:10.13018/BMR30206
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Title: Solution structures of Brd2 second bromodomain in complex with stat3 peptide PubMed: 28262505
Deposition date: 2016-12-07 Original release date: 2017-02-20
Authors: Zeng, L.; Zhou, M.
Citation: Cheung, K.; Zhang, F.; Jaganathan, A.; Sharma, R.; Zhang, Q.; Konuma, T.; Shen, T.; Lee, J.-Y., J.; Ren, C.; Chen, C.-H., C.; Lu, G.; Olson, M.; Zhang, W.; Kaplan, M.; Littman, D.; Walsh, M.; Xiong, H.; Zeng, L.; Zhou, M.. "Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation" Mol. Cell 65, 1068-1080 (2017).
Assembly members:
entity_1, polymer, 112 residues, 13157.136 Da.
entity_2, polymer, 12 residues, 1540.808 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
entity_1: GKLSEQLKHCNGILKELLSK
KHAAYAWPFYKPVDASALGL
HDYHDIIKHPMDLSTVKRKM
ENRDYRDAQEFAADVRLMFS
NCYKYNPPDHDVVAMARKLQ
DVFEFRYAKMPD
entity_2: HNLLRIXQFLQS
- assigned_chemical_shifts
- spectral_peak_list
| Data type | Count |
| 13C chemical shifts | 448 |
| 15N chemical shifts | 100 |
| 1H chemical shifts | 834 |
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