BMRB Entry 30345
Click here to enlarge.
PDB ID: 6b1g
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR30345
MolProbity Validation Chart
NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
NMR-STAR v2.1 text file (deprecated)
XML gzip file.
RDF gzip file.
All files associated with the entry
Title: Solution structure of TDP-43 N-terminal domain dimer. PubMed: 29438978
Deposition date: 2017-09-18 Original release date: 2018-02-21
Authors: Naik, M.; Wang, A.; Conicella, A.; Fawzi, N.
Citation: Wang, Ailin; Conicella, Alexander; Schmidt, Hermann Broder; Martin, Erik; Rhoads, Shannon; Reeb, Ashley; Nourse, Amanda; Ramirez Montero, Daniel; Ryan, Veronica; Rohatgi, Rajat; Shewmaker, Frank; Naik, Mandar; Mittag, Tanja; Ayala, Yuna; Fawzi, Nicolas. "A single N-terminal phosphomimic disrupts TDP-43 polymerization, phase separation and RNA splicing" EMBO J. 37, e97452-e97452 (2018).
Assembly members:
entity_1, polymer, 83 residues, 9244.335 Da.
entity_2, polymer, 83 residues, 9196.318 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
entity_1: GHMMSEYIRVTEDENDEPIE
IPSEDDGTVLLSTVTAQFPG
ACGLRYRNPVEQCMRGVRLV
EGILHAPDAGWGNLVYVVNY
PKD
entity_2: GHMMSERIRVTEDENDEPIE
IPSEDDGTVLLSTVTAQFPG
ACGLRYRNPVSQCMRGVRLV
EGILHAPDAGWGNLVYVVNY
PKD
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 654 |
| 15N chemical shifts | 161 |
| 1H chemical shifts | 1080 |
Additional metadata:
Download simulated HSQC data in one of the following formats:
CSV: Backbone
or all simulated shifts
SPARKY: Backbone
or all simulated shifts