BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 30529

Title: NMR structure of the cNTnC-cTnI chimera bound to calcium desensitizer W7   PubMed: 30376637

Deposition date: 2018-10-24 Original release date: 2018-11-06

Authors: Cai, F.; Hwang, P.; Sykes, B.

Citation: Cai, F.; Hwang, P.; Sykes, B.. "Structural Changes Induced by the Binding of the Calcium Desensitizer W7 to Cardiac Troponin."  Biochemistry 57, 6461-6469 (2018).

Assembly members:
entity_1, polymer, 125 residues, 14186.127 Da.
entity_CA, non-polymer, 40.078 Da.
entity_WW7, non-polymer, 340.868 Da.

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli BL21(DE3)

Entity Sequences (FASTA):
entity_1: MDDIYKAAVEQLTEEQKNEF KAAFDIFVLGAEDGSISTKE LGKVMRMLGQNPTPEELQEM IDEVDEDGSGTVDFDEFLVM MVRSMKDDSKGKFKRPTLRR VRISADAMMQALLGARAKGH HHHHH

Data sets:
Data typeCount
13C chemical shifts391
15N chemical shifts114
1H chemical shifts800

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