BMRB Entry 30543
Chem Shift validation: AVS_anomalous, AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR30543
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Title: NMR solution structure of the homodimeric, autoinhibited state of the CARD9 CARD and first coiled-coil PubMed: 31296852
Deposition date: 2018-11-13 Original release date: 2019-07-12
Authors: Holliday, M.; Fairbrother, W.; Dueber, E.
Citation: Holliday, M.; Witt, A.; Rodriguez Gama, A.; Walters, B.; Arthur, C.; Halfmann, R.; Rohou, A.; Dueber, E.; Fairbrother, W.. "Structures of autoinhibited and polymerized forms of CARD9 reveal mechanisms of CARD9 and CARD11 activation" Nat. Commun. 10, 3070-3070 (2019).
Assembly members:
entity_1, polymer, 142 residues, 16116.458 Da.
entity_ZN, non-polymer, 65.409 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli BL21(DE3)
Entity Sequences (FASTA):
entity_1: GSDYENDDECWSVLEGFRVT
LTSVIDPSRITPYLRQCKVL
NPDDEEQVLSDPNLVIRKRK
VGVLLDILQRTGHKGYVAFL
ESLELYYPQLYKKVTGKEPA
RVFSMIIDASGESGLTQLLM
TEVMKLQKKVQDLTALLSSK
DD
- assigned_chemical_shifts
- spectral_peak_list
| Data type | Count |
| 13C chemical shifts | 1038 |
| 15N chemical shifts | 270 |
| 1H chemical shifts | 1149 |
Additional metadata:
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