BMRB Entry 34069
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PDB ID: 5mgq
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR34069
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Title: Solution structure of oxidized and amidated human IAPP (1-37), the diabetes II peptide. PubMed: 28287098
Deposition date: 2016-11-21 Original release date: 2017-03-23
Authors: Rodriguez Camargo, D.; Tripsianes, K.; Reif, B.
Citation: Rodriguez Camargo, D.; Tripsianes, K.; Buday, K.; Franko, A.; Gobl, C.; Hartlmuller, C.; Sarkar, R.; Aichler, M.; Mettenleiter, G.; Schulz, M.; Boddrich, A.; Erck, C.; Martens, H.; Walch, A.; Madl, T.; Wanker, E.; Conrad, M.; de Angelis, M.; Reif, B.. "The redox environment triggers conformational changes and aggregation of hIAPP in Type II Diabetes." Sci. Rep. 7, 44041-44041 (2017).
Assembly members:
entity_1, polymer, 37 residues, 3908.319 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli BL21(DE3)
Entity Sequences (FASTA):
entity_1: KCNTATCATQRLANFLVHSS
NNFGAILSSTNVGSNTX
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 56 |
| 15N chemical shifts | 42 |
| 1H chemical shifts | 238 |
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