BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 34081

Title: Solution structure of TDP-43 (residues 1-102)   PubMed: 28566288

Deposition date: 2016-12-22 Original release date: 2017-06-02

Authors: Mompean, M.; Romano, V.; Pantoja-Uceda, D.; Stuani, C.; Baralle, F.; Laurents, D.

Citation: Mompean, M.; Romano, V.; Pantoja-Uceda, D.; Stuani, C.; Baralle, F.; Buratti, E.; Laurents, D.. "Point mutations in transactive response DNA-binding protein 43 (TDP-43)'s N-terminal domain compromise its stability, dimerization and functions"  J. Biol. Chem. 292, 11992-12006 (2017).

Assembly members:
entity_1, polymer, 114 residues, 12674.207 Da.

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli

Entity Sequences (FASTA):
entity_1: MAGSHHHHHHGSMSEYIRVT EDENDEPIEIPSEDDGTVLL STVTAQFPGACGLRYRNPVS QCMRGVRLVEGILHAPDAGW GNLVYVVNYPKDNKRKMDET DASSAVKVKRAVQK

Data sets:
Data typeCount
15N chemical shifts1
1H chemical shifts584

Additional metadata:

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