BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 34155

Title: NMR solution structure of U11/U12 65K protein's C-terminal RRM domain (381-516)   PubMed: 29255062

Deposition date: 2017-06-28 Original release date: 2018-01-23

Authors: Norppa, A.; Kauppala, T.; Heikkinen, H.; Verma, B.; Iwai, H.; Frilander, M.

Citation: Norppa, A.; Kauppala, T.; Heikkinen, H.; Verma, B.; Iwai, H.; Frilander, M.. "Mutations in the U11/U12-65K protein associated with isolated growth hormone deficiency lead to structural destabilization and impaired binding of U12 snRNA."  RNA 24, 396-409 (2018).

Assembly members:
entity_1, polymer, 136 residues, 15796.292 Da.

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli

Entity Sequences (FASTA):
entity_1: SDEMPSECISRRELEKGRIS REEMETLSVFRSYEPGEPNC RIYVKNLAKHVQEKDLKYIF GRYVDFSSETQRIMFDIRLM KEGRMKGQAFIGLPNEKAAA KALKEANGYVLFGKPMVVQF ARSARPKQDPKEGKRK

Data sets:
Data typeCount
13C chemical shifts607
15N chemical shifts139
1H chemical shifts968

Additional metadata:

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