BMRB Entry 4456
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR4456
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Title: 1H Chemical Shift Assignments for the cytoplasmic domain of aIIb integrin
Deposition date: 1999-11-13 Original release date: 2000-06-19
Authors: Hwang, P.; Vogel, Hans
Citation: Hwang, P.; Vogel, Hans. "Structures of the Platelet Calcium- and Integrin-binding Protein and the alphaIIb-integrin Cytoplasmic Domain Suggest a Mechanism for Calcium-regulated Recognition; Homology Modeling and NMR Studies" J. Mol. Recognit. 13, 83-92 (2000).
Assembly members:
integrin aIIb, polymer, 25 residues, Formula weight is not available
Natural source: Common Name: human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: chemical synthesis
Entity Sequences (FASTA):
integrin aIIb: VLAMWKVGFFKRNRPPLEED
DEEGE
- assigned_chemical_shifts
| Data type | Count |
| 1H chemical shifts | 149 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | aIIb | 1 |
Entities:
Entity 1, aIIb 25 residues - Formula weight is not available
| 1 | VAL | LEU | ALA | MET | TRP | LYS | VAL | GLY | PHE | PHE | ||||
| 2 | LYS | ARG | ASN | ARG | PRO | PRO | LEU | GLU | GLU | ASP | ||||
| 3 | ASP | GLU | GLU | GLY | GLU |
Samples:
sample_1: integrin aIIb 2.0 mM; TFE 45%
sample_conditions_1: pH: 6.6; temperature: 298 K
Experiments:
| Name | Sample | Sample state | Sample conditions |
|---|---|---|---|
| NOESY | not available | not available | not available |
| TOCSY | not available | not available | not available |
| DQF-COSY | not available | not available | not available |
Software:
nmrDraw -
NMR spectrometers:
- Bruker AMX 500 MHz