BMRB Entry 4700
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PDB ID: 1cf4
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_anomalous, AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR4700
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Title: Structure of Cdc42 bound to the GTPase Binding Domain of PAK
Deposition date: 2000-03-23 Original release date: 2000-12-18
Authors: Morreale, Angela; Venkatesan, Meenakshi; Mott, Helen; Owen, Darerca; Nietlispach, Daniel; Lowe, Peter; Laue, Ernest
Citation: Morreale, Angela; Venkatesan, Meenakshi; Mott, Helen; Owen, Darerca; Nietlispach, Daniel; Lowe, Peter; Laue, Ernest. "Structure of Cdc42 bound to the GTPase Binding Domain of PAK" Nat. Struct. Biol. 7, 384-388 (2000).
Assembly members:
Cdc42, polymer, 185 residues, 20430.40 Da.
p21 activated kinase, polymer, 46 residues, 5127.64 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology
Entity Sequences (FASTA):
Cdc42: MQTIKCVVVGDGAVGKTCLL
ISYTTNKFPSEYVPTVFDNY
AVTVMIGGEPYTLGLFDTAG
LEDYDRLRPLSYPQTDVFLV
CFSVVSPSSFENVKEKWVPE
ITHHCPKTPFLLVGTQIDLR
DDPSTIEKLAKNKQKPITPE
TAEKLARDLKAVKYVECSAL
TQKGLKNVFDEAILAALEPP
EPKKX
p21 activated kinase: GSISLPSDFEHTIHVGFDAV
TGEFTGMPEQWARLLQTSNI
TKSEQK
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 741 |
| 1H chemical shifts | 1550 |
| 15N chemical shifts | 224 |
Additional metadata:
Related Database Links:
| BMRB | 15424 |
| PDB | 1A4R 1AJE 1AM4 1AN0 1CEE 1CF4 1DOA 1E0A 1EES 1GRN 1GZS 1KI1 1KZ7 1KZG 1NF3 2ASE 2DFK 2KB0 2NGR 2ODB 2QRZ 2WM9 2WMN 2WMO 3EG5 3GCG 3QBV 3VHL 4DID 4ITR 4JS0 4YC7 4YDH 1F3M 2QME |
| DBJ | BAB22563 BAC16312 BAC34669 BAC35825 BAE01909 BAC16311.1 BAC16312.1 BAF85787.1 |
| EMBL | CAA90215 CAB57325 CAB57326 CAB57327 CAB57328 CAF91245.1 CAN87991.1 CAN87992.1 CAF94511.1 |
| GB | AAA37410 AAA52494 AAA52592 AAB40051 AAC00027 |
| REF | NP_001003254 NP_001008027 NP_001017070 NP_001018130 NP_001034891 XP_001363384.1 XP_001363301.1 NP_035165.2 NP_001070366.1 XP_508657.2 |
| SP | P60766 P60952 P60953 Q007T2 Q2KJ93 |
| TPG | DAA32122 |
| SWISS-PROT | Q13153 O88643 Q08E52 P35465 |
| PRF | 2003404A |
| GenBank | ACA13260.1 ACA13261.1 EAW75028.1 EDL16325.1 EDM18463.1 |
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