BMRB Entry 50263
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR50263
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Title: NMR backbone assignment of the transmembrane helix of TREM2, an Alzheimer linked disease protein PubMed: 32830336
Deposition date: 2020-05-08 Original release date: 2020-06-08
Authors: Steiner, Andrea; Hagn, Franz
Citation: Steiner, Andrea; Schlepckow, Kai; Brunner, Bettina; Steiner, Harald; Haass, Christian; Hagn, Franz. "gamma-Secretase cleavage of the Alzheimer risk factor TREM2 is determined by its intrinsic structural dynamics" EMBO J. 39, e104247-e104247 (2020).
Assembly members:
entity_1, polymer, 49 residues, Formula weight is not available
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
entity_1: GSGRSLLEGEIPFPPTSILL
LLACIFLIKILAASALWAAA
WHGQKPGTH
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 103 |
| 15N chemical shifts | 32 |
| 1H chemical shifts | 32 |
Additional metadata:
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SPARKY: Backbone
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