BMRB Entry 5186
Chem Shift validation: AVS_anomalous, AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR5186
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Title: 1H, 13C, and 15N backbone assignment of the vascular endothelial growth factor receptor-binding domain PubMed: 11883783
Deposition date: 2001-10-19 Original release date: 2002-05-07
Authors: Pan, Borlan; Fairbrother, Wayne
Citation: Pan, Borlan; Fairbrother, Wayne. "1H, 13C, and 15N Resonance Assignment of the Vascular Endothelial Growth Factor Receptor-binding Domain in Complex with a Receptor-blocking Peptide" J. Biomol. NMR 22, 189-190 (2002).
Assembly members:
vascular endothelial growth factor, polymer, 99 residues, 11625.4 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology
Entity Sequences (FASTA):
vascular endothelial growth factor: HHEVVKFMDVYQRSYCHPIE
TLVDIFQEYPDEIEYIFKPS
CVPLMRCGGCCNDEGLECVP
TEESNITMQIMRIKPHQGQH
IGEMSFLQHNKCECRPKKD
- assigned_chemical_shifts
| Data type | Count |
| 1H chemical shifts | 184 |
| 13C chemical shifts | 260 |
| 15N chemical shifts | 85 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | VEGF subunit 1 | 1 |
| 2 | VEGF subunit 2 | 1 |
Entities:
Entity 1, VEGF subunit 1 99 residues - 11625.4 Da.
| 1 | HIS | HIS | GLU | VAL | VAL | LYS | PHE | MET | ASP | VAL | ||||
| 2 | TYR | GLN | ARG | SER | TYR | CYS | HIS | PRO | ILE | GLU | ||||
| 3 | THR | LEU | VAL | ASP | ILE | PHE | GLN | GLU | TYR | PRO | ||||
| 4 | ASP | GLU | ILE | GLU | TYR | ILE | PHE | LYS | PRO | SER | ||||
| 5 | CYS | VAL | PRO | LEU | MET | ARG | CYS | GLY | GLY | CYS | ||||
| 6 | CYS | ASN | ASP | GLU | GLY | LEU | GLU | CYS | VAL | PRO | ||||
| 7 | THR | GLU | GLU | SER | ASN | ILE | THR | MET | GLN | ILE | ||||
| 8 | MET | ARG | ILE | LYS | PRO | HIS | GLN | GLY | GLN | HIS | ||||
| 9 | ILE | GLY | GLU | MET | SER | PHE | LEU | GLN | HIS | ASN | ||||
| 10 | LYS | CYS | GLU | CYS | ARG | PRO | LYS | LYS | ASP |
Samples:
Sample_1: vascular endothelial growth factor, [U-98% 13C; U-98% 15N], 1.0 mM
Sample_2: vascular endothelial growth factor, [U-98% 13C; U-98% 15N], 2.0 mM
Cond_1: pH: 7.0; temperature: 318 K
Experiments:
| Name | Sample | Sample state | Sample conditions |
|---|
Software:
No software information available
NMR spectrometers:
- Bruker AMX 500 MHz
- Bruker DRX 800 MHz
Related Database Links:
| BMRB | 5198 |
| PDB | |
| DBJ | BAA78418 BAB68520 BAD92722 BAG70136 BAG70265 |
| EMBL | CAA09179 CAA44447 CAA57143 CAB82426 CAC19923 |
| GB | AAA35789 AAA36804 AAA36807 AAB47118 AAC63102 |
| PRF | 2105202A |
| REF | NP_001003175 NP_001009854 NP_001020537 NP_001020538 NP_001020539 |
| SP | P15692 P49151 Q9MYV3 |
Download simulated HSQC data in one of the following formats:
CSV: Backbone
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SPARKY: Backbone
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