BMRB Entry 5327
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR5327
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Title: Structural basis for Hif-1alpha/CBP recognition in the cellular hypoxic response PubMed: 11959977
Deposition date: 2002-03-19 Original release date: 2002-06-13
Authors: Dames, Sonja; Martinez-Yamout, Maria; De Guzman, Roberto; Dyson, H. Jane; Wright, Peter
Citation: Dames, Sonja; Martinez-Yamout, Maria; De Guzman, Roberto; Dyson, H.; Wright, Peter. "From the Cover: Structural basis for Hif-1alpha/CBP Recognition in the Cellular Hypoxic Response" Proc. Natl. Acad. Sci. U.S.A. 99, 5271-5276 (2002).
Assembly members:
hypoxia induced factor 1 alpha, polymer, 51 residues, Formula weight is not available
CREB-binding protein, polymer, 95 residues, Formula weight is not available
ZN, non-polymer, 65.409 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
hypoxia induced factor 1 alpha: SDLACRLLGQSMDESGLPQL
TSYDCEVNAPIQGSRNLLQG
EELLRALDQVN
CREB-binding protein: ADPEKRKLIQQQLVLLLHAH
KCQRREQANGEVRACSLPHC
RTMKNVLNHMTHCQAGKACQ
VAHCASSRQIISHWKNCTRH
DCPVCLPLKNASDKR
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 467 |
| 15N chemical shifts | 154 |
| 1H chemical shifts | 939 |
Additional metadata:
Related Database Links:
| BMRB | 5306 5987 6268 |
| PDB | 1H2K 1H2L 1H2M 1L3E 1L8C 2ILM 1R8U 1U2N |
| DBJ | BAA78675 BAC28305 BAC28578 BAC36320 BAE01417 BAE06125 BAG65526 |
| EMBL | CAA64833 CAA70305 CAA70306 CAA70701 CAG29396 |
| GenBank | AAC50152 AAC51210 AAC52730 AAC53455 AAC53461 AAB28651 AAC08447 AAC51331 AAC51770 AAH72594 |
| PRF | 2114407A 1923401A |
| REF | NP_001076251 NP_001116596 NP_001521 NP_034561 NP_077335 NP_001020603 NP_001073315 NP_004371 NP_596872 XP_001095225 |
| SWISS-PROT | O35800 Q0PGG7 Q16665 Q309Z6 Q61221 P45481 Q92793 |
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