BMRB Entry 7147
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PDB ID: 2h7b
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_anomalous, AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR7147
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Title: The acute myeloid leukemia fusion protein AML1-ETO targets E-proteins via a PAH-like TAFH domain PubMed: 16803958
Deposition date: 2006-05-18 Original release date: 2006-10-30
Authors: Plevin, M.; Zhang, J.; Guo, C.; Roeder, R.; Ikura, M.
Citation: Plevin, M.; Zhang, J.; Guo, C.; Roeder, R.; Ikura, M.. "The acute myeloid leukemia fusion protein AML1-ETO targets E proteins via a paired amphipathic helix-like TBP-associated factor homology domain" Proc. Natl. Acad. Sci. U.S.A. 103, 10242-10247 (2006).
Assembly members:
Core-binding factor, ML1-ETO, polymer, 105 residues, Formula weight is not available
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
Core-binding factor, ML1-ETO: GSARQLSKLKRFLTTLQQFG
NDISPEIGERVRTLVLGLVN
STLTIEEFHSKLQEATNFPL
RPFVIPFLKANLPLLQRELL
HAARLAKQNPAQYLAQHEQL
LLDAS
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 326 |
| 15N chemical shifts | 96 |
| 1H chemical shifts | 768 |
Additional metadata:
Related Database Links:
| BMRB | 16467 7396 |
| PDB | 2H7B 2KNH 2PP4 |
| DBJ | BAA03089 BAA03247 BAA03558 BAA03559 BAA03560 |
| EMBL | CAA56311 CAF99400 CAG33073 |
| GB | AAB34819 AAB34820 AAC28931 AAC28932 AAC28933 |
| REF | NP_001070244 NP_001089065 NP_001101923 NP_001102127 NP_001104496 |
| SP | O75081 Q06455 Q61909 |
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