BMRB Entry 7420
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PDB ID: 2jgw
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_anomalous, AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR7420
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Title: STRUCTURE OF CCP MODULE 7 OF COMPLEMENT FACTOR H- THE AMD AT RISK VARIENT (402H) PubMed: 17360715
Deposition date: 2008-03-06 Original release date: 2008-08-08
Authors: Herbert, A.; Deakin, J.; Schmidt, C.; Blaum, B.; Egan, C.; Ferreira, V.; Pangburn, M.; Lyon, M.; Uhrin, D.; Barlow, P.
Citation: Herbert, A.; Deakin, J.; Schmidt, C.; Blaum, B.; Egan, C.; Ferreira, V.; Pangburn, M.; Lyon, M.; Uhrin, D.; Barlow, P.. "Structure Shows Glycosaminoglycan- and Protein-Recognition Site in Factor H is Perturbed by Age-Related Macular Degeneration-Linked single nucleotide polymorphism" J. Biol. Chem. 282, 18960-18968 (2007).
Assembly members:
COMPLEMENT_FACTOR_H, polymer, 65 residues, Formula weight is not available
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: PICHIA PASTORIS
Entity Sequences (FASTA):
COMPLEMENT_FACTOR_H: EAAGLRKCYFPYLENGYNQN
HGRKFVQGKSIDVACHPGYA
LPKAQTTVTCMENGWSPTPR
CIRVK
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 275 |
| 15N chemical shifts | 68 |
| 1H chemical shifts | 439 |
Additional metadata:
Related Database Links:
| BMRB | 7421 |
| PDB | 2IC4 2JGW 2JGX 2UWN 2V8E 2W80 2W81 4AYD 4AYE 4AYI 4AYM |
| EMBL | CAA30403 CAB41739 |
| GB | AAA52013 AAH37285 AAI10644 ADZ15369 AHH32464 |
| REF | NP_001014975 XP_004028137 |
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