BMRB Entry 16496
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PDB ID: 2knc
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS, SPARTA
BMRB Entry DOI: doi:10.13018/BMR16496
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Title: PLATELET INTEGRIN ALFAIIB-BETA3 TRANSMEMBRANE- CYTOPLASMIC HETEROCOMPLEX PubMed: 19805198
Deposition date: 2009-09-15 Original release date: 2009-12-18
Authors: Yang, Jun; Ma, Yan-Qing; Page, Richard; Misra, Saurav; Plow, Edward; Qin, Jun
Citation: Yang, Jun; Ma, Yan-Qing; Page, Richard; Misra, Saurav; Plow, Edward; Qin, Jun. "Structure of an integrin alphaIIb beta3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation." Proc. Natl. Acad. Sci. U.S.A. 106, 17729-17734 (2009).
Assembly members:
AIIbTMCD, polymer, 54 residues, 5653.673 Da.
B3TMCD, polymer, 79 residues, 8371.900 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
AIIbTMCD: GAMGSEERAIPIWWVLVGVL
GGLLLLTILVLAMWKVGFFK
RNRPPLEEDDEEGE
B3TMCD: GAMGSKGPDILVVLLSVMGA
ILLIGLAALLIWKLLITIHD
RKEFAKFEEERARAKWDTAN
NPLYKEATSTFTNITYRGT
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 529 |
| 15N chemical shifts | 140 |
| 1H chemical shifts | 860 |
Additional metadata:
Related Database Links:
| BMRB | 16497 15552 16771 17930 17932 |
| PDB | 2K1A 2K9J 2KNC 1M8O 1S4X 2KV9 2LJD 2LJF |
| DBJ | BAG37735 BAI46167 BAE34283 BAG62151 BAJ17755 |
| EMBL | CAA29987 CAD29521 |
| GB | AAA52597 AAA53150 AAA60114 AAA65936 AAI17444 AAA35927 AAA52589 AAA52600 AAA60122 AAB27096 |
| PRF | 1403305A |
| REF | NP_000410 XP_001114526 XP_001150497 XP_002827479 XP_003282434 NP_000203 NP_001003162 NP_001075271 NP_001075535 NP_001193419 |
| SP | P08514 P53711 O54890 P05106 |
| TPG | DAA18403 |
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