BMRB Entry 19977
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PDB ID: 2mpf
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR19977
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Title: Solution structure human HCN2 CNBD in the cAMP-unbound state
Deposition date: 2014-05-16 Original release date: 2014-09-02
Authors: Saponaro, Andrea; Pauleta, Sofia; Cantini, Francesca; Matzapetakis, Manolis; Hammann, Christian; Banci, Lucia; Thiel, Gerard; Santoro, Bina; Moroni, Anna
Citation: Saponaro, Andrea; Pauleta, Sofia; Cantini, Francesca; Matzapetakis, Manolis; Hammann, Christian; Banci, Lucia; Thiel, Gerard; Santoro, Bina; Moroni, Anna. "Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function" Not known ., .-..
Assembly members:
entity, polymer, 158 residues, 15918.672 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
entity: GPSSPMELNGPLREEIVNFN
CRKLVASMPLFANADPNFVT
AMLTKLKFEVFQPGDYIIRE
GTIGKKMYFIQHGVVSVLTK
GNKEMKLSDGSYFGEICLLT
RGRRTASVRADTYCRLYSLS
VDNFNEVLEEYPMMRRAFET
VAIDRLDRIGKKNSILLH
- assigned_chemical_shifts
| Data type | Count |
| 1H chemical shifts | 1113 |
| 13C chemical shifts | 624 |
| 15N chemical shifts | 149 |
Additional metadata:
Related Database Links:
| PDB | 1Q3E 2MPF 2Q0A 3BPZ 3ETQ 3FFQ 3U10 |
| DBJ | BAD32628 BAI44633 BAI45607 |
| EMBL | CAA12406 CAB42602 CAB42630 |
| GB | AAC28444 AAC39760 AAC40125 AAF62174 AAI18002 |
| REF | NP_001185 NP_032252 NP_446136 XP_002193445 XP_002689207 |
| SP | O88703 Q9JKA9 Q9UL51 |
| TPG | DAA27526 |
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