Biological Magnetic Resonance Data Bank

A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

BMRB Entry 26516

Title: Transient small molecule interactions kinetically modulate amyloid b peptide self-assembly   PubMed: 23058290

Authors: Abelein, Axel; Lang, Lisa; Lendel, Christofer; Graslund, Astrid; Danielsson, Jens

Citation: Abelein, Axel; Lang, Lisa; Lendel, Christofer; Graslund, Astrid; Danielsson, Jens. "Transient small molecule interactions kinetically modulate amyloid b peptide self-assembly"  FEBS Lett. 586, 3991-3995 (2012).

Assembly members:
amyloid_B, polymer, 40 residues, Formula weight is not available
sodium 3,3'-(1E,1'E)-biphenyl-4,4'-diylbis(diazene-2,1-diyl)bis(4-aminonaphthalene-1-sulfonate), non-polymer, 696.663 Da.

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli

Entity Sequences (FASTA):

Data sets:
Data typeCount
T2 relaxation values23

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all


Entity Assembly IDEntity NameEntity ID
1amyloid B1
2Congo Red2


Entity 1, amyloid B 40 residues - Formula weight is not available


Entity 2, Congo Red - C32 H22 N6 Na2 O6 S2 - 696.663 Da.

1   CGO


sample_1: amyloid B, [U-100% 15N], 50 uM; NaOH 10 mM; sodium-phosphate buffer 10 mM; Congo Red 166.67 uM; H2O 90%; D2O 10%

sample_conditions_1: temperature: 276 K; pH: 7.4; pressure: 1 atm


NameSampleSample stateSample conditions
1H-15N HSQC 1sample_1isotropicsample_conditions_1


NMRPipe, Delaglio, Grzesiek, Vuister, Zhu, Pfeifer and Bax - processing

SPARKY, Goddard - data analysis

NMR spectrometers:

  • Bruker Avance 700 MHz

Related Database Links:

BMRB 11435 15775 17159 17186 17764 17793 17794 17795 17796 18052 18127 18128 18129 18131 19009 19309 19393 25218 25289 25429 26508
DBJ BAA22264 BAA84580 BAB71958 BAD51938 BAE01907
EMBL CAA30050 CAA31830 CAA39589 CAA39590 CAA39591
GB AAA35540 AAA36829 AAA51564 AAA51722 AAA51726
PIR A60045 D60045 E60045 G60045 PQ0438
PRF 1303338A 1403400A 1405204A 1507304A 1507304B
REF NP_000475 NP_001006601 NP_001013036 NP_001070264 NP_001127014
SP P05067 P53601 P79307 P86906 Q28053
TPG DAA33655