BMRB Entry 30258
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PDB ID: 5uzz
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR30258
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Title: Structure of wild type pre-miR21 apical loop PubMed: 28437065
Deposition date: 2017-02-27 Original release date: 2017-06-08
Authors: Shortridge, M.; Varani, G.
Citation: Shortridge, M.; Walker, M.; Pavelitz, T.; Chen, Y.; Yang, W.; Varani, G.. "A macrocyclic peptide ligand binds the oncogenic microRNA-21 precursor and suppresses Dicer processing." ACS Chem. Biol. 12, 1611-1620 (2017).
Assembly members:
entity_1, polymer, 31 residues, 9912.896 Da.
entity_2, polymer, 14 residues, 1812.225 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: chemical synthesis
Entity Sequences (FASTA):
entity_1: GGUGUUGACUGUUGAAUCUC
AUGGCAACACC
entity_2: RVRTRGKRRIRRXP
- assigned_chemical_shifts
| Data type | Count |
| 15N chemical shifts | 13 |
| 1H chemical shifts | 244 |