BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 6347

Title: Evidence for domain-specific recognition of SK and Kv channels by MTX and HsTx1 scorpion toxins   PubMed: 15498765

Authors: Regaya, I.; Beeton, C.; Ferrat, G.; Andreotti, N.; Chandy, G.; Darbon, H.; De Waard, M.; Sabatier, J.

Citation: Regaya, I.; Beeton, C.; Ferrat, G.; Andreotti, N.; Darbon, H.; De Waard, M.; Sabatier, J.. "Evidence for domain-specific recognition of SK and Kv channels by MTX and HsTx1 scorpion toxins"  J. Biol. Chem. 279, 55690-55696 (2004).

Assembly members:
MTx-HsTx1, polymer, 34 residues, Formula weight is not available

Natural source:   Common Name: Asian forest scorpions   Taxonomy ID: 118530   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Heterometrus spinifer

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):
MTx-HsTx1: VSCTGSKDCYAPCRKQTGCP YGKCMNRKCKCNRC

Data sets:
Data typeCount
1H chemical shifts158

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1MTx-HsTx11

Entities:

Entity 1, MTx-HsTx1 34 residues - Formula weight is not available

1   VALSERCYSTHRGLYSERLYSASPCYSTYR
2   ALAPROCYSARGLYSGLNTHRGLYCYSPRO
3   TYRGLYLYSCYSMETASNARGLYSCYSLYS
4   CYSASNARGCYS

Samples:

sample_1: MTx-HsTx1 mM

sample_cond_1: pH: 3; temperature: 300 K

Experiments:

NameSampleSample stateSample conditions
DQF-COSYnot availablenot availablenot available
2D TOCSYnot availablenot availablenot available
2D NOESYnot availablenot availablenot available

Software:

xwinnmr v2.0 - processing

XEASY v1.3.13 - data analysis

DIANA v2.8 - structure solution

CNS v1.1 - refinement

NMR spectrometers:

  • Bruker DMX 500 MHz

Related Database Links:

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