BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 6467

Title: Solution structure of APETx2, a specific peptide inhibitor of ASIC3 proton-gated channels   PubMed: 15987885

Authors: Chagot, Benjamin; Escoubas, Pierre; Diochot, Sylvie; Bernard, Cedric; Lazdunski, Michel; Darbon, Herve

Citation: Chagot, Benjamin; Escoubas, Pierre; Diochot, Sylvie; Bernard, Cedric; Lazdunski, Michel; Darbon, Herve. "Solution structure of APETx2, a specific peptide inhibitor of ASIC3 proton-gated channels"  Protein Sci. 14, 2003-2010 (2005).

Assembly members:
Anthopleura elegantissima toxin 2, polymer, 42 residues, Formula weight is not available

Natural source:   Common Name: clonal anemone   Taxonomy ID: 6110   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Anthopleura elegantissima

Experimental source:   Production method: purified from the natural source

Entity Sequences (FASTA):
Anthopleura elegantissima toxin 2: GTACSCGNSKGIYWFYRPSC PTDRGYTGSCRYFLGTCCTP AD

Data sets:
Data typeCount
1H chemical shifts217

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1APETx21

Entities:

Entity 1, APETx2 42 residues - Formula weight is not available

1   GLYTHRALACYSSERCYSGLYASNSERLYS
2   GLYILETYRTRPPHETYRARGPROSERCYS
3   PROTHRASPARGGLYTYRTHRGLYSERCYS
4   ARGTYRPHELEUGLYTHRCYSCYSTHRPRO
5   ALAASP

Samples:

sample_1: Anthopleura elegantissima toxin 2 1.32 mM

ex-cond_1: pH: 3.0; temperature: 280 K

Experiments:

NameSampleSample stateSample conditions
COSYnot availablenot availablenot available
TOCSYnot availablenot availablenot available
NOESYnot availablenot availablenot available

Software:

xwinnmr -

NMR spectrometers:

  • BRUKER DRX 500 MHz

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